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However, the mitochondria-ER contact sites role mediating immune responses through facilitation of the NOD-like receptor protein 3 (NLRP3)-inflammasome assembly are well known, including second messenger mechanisms such as mitochondrial ROS (136, 137)

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"It is a big dataset now because we've been in the field several times talking to between 1,000 and 2,000 young people each time going down to the age of 11 and up to the age of 16," Professor Hastings said

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