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The resulting oxidative stress triggers the transcription factor NF-B, leading to upregulated release of pro-inflammatory cytokines (e.g., IL-6, TNF- ) and chemokines that drive inflammation in the respiratory tract (52)

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While there are vaping products specifically designed to prevent fires and explosions, they arent currently allowed in the U.S

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Controlling these conditions helps protect the vocal cords and may improve overall voice quality

Long-term use of nonsteroidal anti-inflammatory drugs (aspirin and ibuprofen) and infection with bacteria such as H