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In vivo studies Pulmonary toxicity A PMI study on chronic exposure of A/J Mice for 18 months to IQOS smoke showed that IQOS significantly reduced toxicity and carcinogenicity on red blood cell profile, liver function, lung inflammation, emphysematous, and histopathological changes compared to CS in respiratory tract organs 41

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Annotation and expression analysis of cuticular proteins from the tobacco hornworm, Manduca sexta

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Though it was not in the manner of Bergmans choosing, Wigand said his piece and ultimately helped lead to the tobacco companies settling a lawsuit for $246 billion