Diacetyl, in particular, is notorious for causing bronchiolitis obliterans, a debilitating lung disease more commonly known as popcorn lung. This irreversible condition leads to scarring in the tiny airways of the lungs, causing chronic coughing, wheezing, and severe shortness of breath
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Recently, the first longitudinal study on telomere dynamics and COPD has shown an accelerated telomere shortening in patients compared to age-matched smoker controls over a 3-year period of follow-up 201
