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Dapagliflozin mainly undergoes glucuronidation by UGT enzymes, particularly UGT1A9 ( Canagliflozin is primarily glucuronidated by UGT1A9 and UGT2B4, forming inactive O-glucuronide metabolites, with minimal oxidative metabolism by CYP3A4 (Table 1 and Figure 2 provide an overview of the main cytochromes involved in the metabolism of pioglitazone, canagliflozin, and dapagliflozin and possible interactions with tobacco smoke

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These colors can mimic blood during the procedure, potentially leading to false findings

BAT said that evidence from other markets, including Canada and the European Union where similar bans have been imposed, demonstrate little impact on overall cigarette consumption