Recent studies on brain circulation have provided evidence that CBF is impaired by decreased formation of NO from endothelial cells, autonomic nitrergic nerves or brain neurons and also by increased production of ROS
Monia Raffa (Research Laboratory of "Trace elements, free radicals and antioxidants", Biophysical Department, Faculty of Medicine, Monastir, Tunisia) for her help and assistance during biochemical analysis
Because oxidative stress is a common thread in aging and many chronic conditions, and glutathione is one of the body's main defenses against it
Hydrogen sulfide inhibits gene expression associated with aortic valve degeneration by inducing NRF2-related pro-autophagy effect in human aortic valve interstitial cells
It is commonly used to treat and prevent vitamin B deficiencies, improve nerve health, and support energy metabolism
These mitochondrial impairments not only compromise energy production but also act as pro-inflammatory stimuli, promoting chronic neuroinflammation through dysregulated mitochondrial signaling and innate immune response