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Mark Twain, the eminent American wit, once proclaimed: If smoking is not allowed in heaven, I shall not go. While tobacco smoking has itself fallen out of the cultural fashion a 2021 report from the US Centers for Disease Control and Prevention found that 11.5% of Americans over the age of 18 smoked cigarettes, compared with 20.9% in 2005 the plants active stimulant, nicotine, is enjoying a fresh vogue in a new form

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However, relatively little is known about risk factors for PM deficits in PWH [3]