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And the total number of middle school and high school students who tried e-cigarettes in 2012 topped 1.78 million, according to the CDC, despite the fact that 41 US states have laws that prevent minors from purchasing e-cigarettes

Law enforcement officers may also use at-home drug tests in the field to test individuals for the presence of illegal substances

It partially stimulates nicotine receptors in the brain, providing some of the effects of nicotine to ease withdrawal and cravings

[62] Vaping generates more surrounding air levels of particulate matter and nicotine in indoor areas than background air levels

Three numbers underpin this page, all from US government or nonprofit primary sources, checked July 16, 2026

Cigarettes have also been used as a form of therapy and as a way to cope with stress and anxiety