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From a harm-reduction standpoint, nicotine patches are often considered one of the cleaner options because they avoid combustion, inhalation, flavorings, and many oral additives

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The demographic characteristics of the safety population are summarised in Table 1

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Reducing smoking-related harm at the population level depends not only on the potential reduction in risk to the individual who switches from cigarettes to the smoke-free product, but also its adoption by adult smokers