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extraversion was associated with smoking, and smokers tended to be sociable, impulsive, risk taking, and excitement-seeking individuals

Closed systems are those that cannot be taken apart, have the tank refilled, or be altered by the user

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For instance in the bottom picture below, you can see where there are still a few yellow spots

Also, direct information on individual CO levels would have been helpful, though we found some evidence that lower ANA prevalence was associated with cigarette brands having higher CO content, which provides additional indirect support for our hypothesis