Graham James, the inquiry's chair, said opportunities to stop the doctor's behaviour were repeatedly missed by a system characterized by "wilful blindness." "Eight years passed between medical professionals raising concerns about Ian Paterson's medical practice and his suspension," James said
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[17] found that transcriptional factors Snail1 and Twist were upregulation and nuclear translocation in smokers and current-smoking COPD, and their expression is closely associated with EMT activity (S100A4 expression) and the levels of airflow obstruction
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