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However this study did not collect pre-quit data on withdrawal symptoms and did not use ecological momentary assessment, which collects data from participants multiple times a day as they go about their daily lives

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Because acetylcholine acts on both sweat and salivary glands, hypohidrosis (too little sweating) is often accompanied by dry mouth

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This is because CO displaces O 2 from hemoglobin forming carboxyhemoglobin (CO affinity for hemoglobin is 200 times that of O 2 ) and shifting the oxygen dissociation curve to the left, thereby causing hypoxia and impairment of cellular respiration [76]