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Excessive nicotine intake may lead to side effects such as nausea, dizziness, elevated heart rate, and increased blood pressure

Juul contains among the highest nicotine content of any e-cigarette, the CDC noted

If high taxes on readily available goods create illegal markets, just imagine what happens under restrictions and outright bans that make products available only from illegal sources

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[6] Thus, in proving that a framework convention was needed for tobacco control, treaty advocates invoked tobacco-related issues that could not be resolved by the actions of individual countries, such as the smuggling of tobacco and the leakage of tobacco advertisements from countries which lacked stringent regulation to those with restrictions on where and to whom tobacco companies could market their products