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There is an observable decrease, of around 10%, in the duration of exercise until exhaustion in smokers, which is attributable to a reduction in O2 production in the metabolically active tissues, as a result of arterial O2 desaturation, and to the insufficiency of the O2 transportation, supply and uptake system ( Figure 2 )

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The total height is just shy of 4 inches, and the width is about 2 1/2 inches across

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