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In anaerobic environments, it produces nitric oxide (NO), which inhibits cytochrome c oxidase and reduces ATP production in non-replicating Mtb cells (Pstragowski, Zbrzezna, and Bujalska-Zadrozny, 2017

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Effect of the cigarette smoke component, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), on physiological and molecular parameters of thiamin uptake by pancreatic acinar cells