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Estrogen, through its widespread receptors in brain areas of relevance to the addiction circuitry, can influence neurotransmission, lead researcher Erika Comasco, PhD, assistant professor in the Department of Womens and Childrens Health, Neuropsychopharmacology at Uppsala University in Sweden, told Healthline

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Air inside the fuel tank prevents butane gas from being injected into the tank and causes the lighter to malfunction