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The levels of within-subject cotinine normalized for the number of cigarettes smoked will be used to measure the degree of compliance using the RNC cigarettes ([plasma cotinine/CPD (end of randomization)]/[plasma cotinine/CPD (baseline)]) as first described by Benowitz et al

Mixing it with a stimulant sends chaotic, mixed signals to your brain and nervous system

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DNA Mutation in Lung Cells Smoking introduces toxic particles that attack the DNA in lung cells

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