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The molecular mechanisms underlying COVID-19 vaccine-induced GD remain under investigation, but several hypotheses are plausible

Loss of PPAR function in hepatocytes initiates DNA hypermethylation of genes related to fatty acid, bile acid, and steroid hormone receptors, including PPAR, leading to progression of disease [339]

Reduced muscle strength is beginning to feel more like the default, rather than a symptom of a bad day or rough nights sleep

Am J Lifestyle Med 7:395404 Sanyal AJ, Chalasani N, Kowdley KV, McCullough A, Diehl AM, Bass NM, Neuschwander-Tetri BA, Lavine JE, Tonascia J, Unalp A, Van Natta M, Clark J, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR, Nash CRN (2010) Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis

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