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Vitamin B6 (pyridoxine, 2550mg daily) is another low-risk adjunct that some patients report helps

It is studied in animal models of tendon, ligament, GI and vascular healing (200+ PubMed publications)

Possible causes include brain infection (viral encephalitis, subacute sclerosing panencephalitis, Whipple's disease) or inflammation (limbic encephalitis, Hashimoto's encephalopathy, cerebral vasculitis)

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The three-amino-acid truncation transforms IGF-1 from a highly regulated, IGFBP-bound mediator into a potent, locally-acting growth factor with minimal systemic distribution