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Ratings Participants rated their fear when confronted with CS+ and CS on a continuous scale between 1 (no fear/stress) and 10 (very much fear/stress) before and after the acquisition phase on day 1, as well as before and after the generalization test on day 2

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This enabled us to investigate the effects on endothelial cells of substances in smoke/aerosol that are absorbed through the lungs and enter the bloodstream, and also any other circulating molecules that the body might produce in response to inhaling the smoke and/or aerosol, including proteins involved in the inflammatory response. The study included 120 adults, ages 21-50 years without cardiovascular disease