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FDA, Preliminary Scientific Evaluation of the Possible Public Health Effects of Menthol versus Nonmenthol Cigarettes

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The evidence shows: The amount of nicotine inhaled from NVP can be very variable between 0.5 and 4 mg with 15 puffs (in comparison, the amount of nicotine per combustible cigarette is 0.5 to 1.5 mg) 105 Blood concentrations similar to or greater than combustible cigarettes are attainable with liquid nicotine concentrations of 20 mg/mL

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This is yet further evidence of the negative effects of smoking in pregnancy." The researchers stressed that their research was a pilot study and that larger studies were needed to confirm and further understand the relationship between maternal smoking, stress, depression and fetal development