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Cardiovascular Complications Smoking is a major risk factor for heart disease and stroke

59 Data Sources: A PubMed search was completed in clinical queries using the key terms smoking, tobacco, cessation, treatment, therapy, counseling, and medications

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The signs and symptoms of tobacco addiction include strong cravings, increased tolerance, irritability or anxiety when not using tobacco, using tobacco to relieve stress, neglecting responsibilities, and failed attempts to quit

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45 The USPSTF does not recommend for or against the use of e-cigarettes for smoking cessation, citing insufficient evidence and the need for ongoing studies