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Because clozapine is primarily metabolized by CYP1A2 (approximately 70%), smoking can induce clozapine metabolism and abruptly stopping smoking can increase clozapine levels
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Thus, this database is likely to be a valuable resource for the researchers with interest in chemical profiling of SLT products
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On logistic regression (Table 4) to determine significant factors influencing the use of SLTs, the greatest odds of use were found with use as an alternative to cigarettes (OR 4.45) and secondly, due to its availability in a liked flavor (OR 2.27)