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Anisimov et al., 2001 Demonstrated antioxidant protection and normalization of circadian rhythm

Due to BVs short duration of action and the challenge of estimating its dosages, scientists and professionals have promoted and created alternate options, such as mixing polymers or nanoparticles (NPs) (Ojha et al., 2023

Metformin, the current first-line treatment in T2DM, has an unclear antidepressant effect [166] despite identified direct mechanisms and pleiotropic effects, including inhibition of angiotensin II and NF-B factor, normalization of gut microbiota, and intestinal permeabilization, and in vivo experimental data [167] supporting its potential benefits

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BPC-157 has been shown in research to alleviate leaky gut, IBS, intestinal cramps, and Crohns disease by acting on many pathways in the digestive tract