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The risks of exposure during the first trimester are not clearly established

Most of the evidence comes from laboratory smoke testing and chemical analysis

Many early-life risk factors could be prevented, such as poor nutrition, low physical activity, early alcohol consumption, and exposure to smoking and biomass fumes

While lacking the artistic or fashion appeal of the Zippo, disposable lighters were perfect for a fast-moving, money conscious society, as they did not require refills and could be easily discarded

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