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As seen in the chart below, the use of traditional cigarettes among youth in North Carolina was declining until the introduction of e-cigarettes in 2011 interrupted this trend

however endogenous ligands that have demonstrated activity at these receptors also have activity for GPR119 [74]

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The targeted marketing of menthol cigarettes to Black individuals has contributed to about 77% of Black smokers using menthol cigarettes, compared to 23% of white smokers

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