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At the 85th percentile of exposure, the mean RR of COPD was 6.01 (2.0818.58)

When given i.v

For the average user or casual smoker, 5% nicotine may be more than necessary and could lead to unpleasant side effects like dizziness or throat irritation

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They all look the same

While the pouches don't contain cancer-causing tobacco, Zyn is quite addictive and it has raised alarm bells among regulators who worry that it is being marketed to underage users