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Abstract Positron emission tomography (PET) has convincingly provided in vivo evidence that psychoactive drugs increase dopamine (DA) levels in human brain, a feature thought critical to their reinforcing properties

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These same authors, in another randomised, double-blind, placebo-controlled study, analysed the efficacy of sublingual nicotine tablets in 2 groups of patients: one that received intensive CBT and another that received mild intensity CBT

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