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Its connection to cancer, heart attacks and chronic lung disease is beyond doubt, he says

HIF-2 showed a trend towards downregulation by CSE but the effect was not as pronounced as for HIF-1 (Fig

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North America remains the largest market, while the Asia-Pacific region is recognized as the fastest-growing area for luxury cigarettes

Nevertheless, given some participants difficulty in interpreting more metaphoric messages, further work is required to test alternative executions and assess whether message novelty, immediacy or salience is the best determinant of effectiveness

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