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The dose-response relationship is consistent: more smoking, faster progression

We have maintained our momentum by driving further geographic expansion and through continued innovation, including the launch of our fusion and sensations ranges, tailored to meet the needs of local consumer tastes and preferences

[1] Nicotine is metabolized in the liver to cotinine, which stays in the body longer than nicotine

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Bowling, Senior Vice President, Assistant to the Chairman of the Board, Philip Morris Incorporated, to William Kloepfer, Jr., Senior Vice President, The Tobacco Institute, Inc

Its when nicotine is combined with oxygen that it turns into a yellowish substance