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In high-level arsenic exposures, onset of neuropathy may occur after 7 to 14 days, with intense increased sweating in the distal lower extremities, muscle cramps, muscle tenderness, numbness, paresthesia, and spontaneous pain [Bleecker 2007]

During a public appearance on May 16, Kim Jong Un appeared visibly tired, with prominent dark circles around his eyes

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and acute myeloid leukemia)

This disease is known for its ability to metastasize, or spread from the origin site to other parts of the body, after starting in the lungs