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Three days later, a car carrying her 15-year-old brother Michael crashed into a lorry along a foggy Oxfordshire road

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Cotinine is generally used as a marker for nicotine exposure

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Although more research is likely necessary to see why that is and whether its true Mayne will soon publish a study devoted to that one possible explanation is that the economic pressures of a cigarette price increase provide a stronger incentive to quit than placing limits on smoking in public places