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The heat also sets off chemical reactions in the solution

Nicotine increases ventricular vulnerability to fibrillation in hearts with healed myocardial infarction

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Fujikane et al., Combination Effect of Caffeine and Cisplatin on a Cisplatin Resistanc Human Lung Cancer Cell Line, Gan To Kagaku Ryoho, July 1990:17(7): 133943

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