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Second-hand smoke from a burning tobacco cigarette has shown to be toxic and include a relative volume of the poisonous chemicals which comprise the cigarette

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doi:10.4103/0976-0105.177703 pmid:27057123 Nelson AC, Williams SB, Pistorius SS, Park HJ, Woodward TJ, Payne AJ, Obray JD, Shin SI, Mabey JK, Steffensen SC (2018) Ventral tegmental area GABA neurons are resistant to GABA(A) receptor-mediated inhibition during ethanol withdrawal

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doi:10.1021/es00016a023 Li X, Lin B, Zhang H, Xie F, Ta N, Tian L et al (2016) Cytotoxicity and mutagenicity of sidestream cigarette smoke particulate matter of different particle sizes