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The chances of someone having these severe side effects depend on the individual patient, their metabolism, age, previous medical conditions, and any idiosyncrasy due to drug interactions

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at the provider level , time constraints, limited training, and reliance on brief, generic advice often limit effective intervention

Unfortunately, these drugs can be too expensive for some

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This rapid onset of effect has also been reported in previous real-world evaluations, suggesting that cytisines partial agonist mechanism suppresses early craving, which may contribute to its high adherence and satisfaction rates