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Follow-up tests may be needed

Kinoshita et al., 2013)

On the other hand, it has been shown that the functional polarization of alveolar macrophages can lead to decreased TLR2 expression in smokers and patients with COPD, which may lead to a locally impaired immune response that contributes to bacterial colonization of the airways [68]

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At this later time point, the majority of alternatively regulated pathways indicated the development of a pro-carcinogenesis phenotype that complemented observations in the adjacent dpHBECs