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In vitro models have been employed to examine differential gene expression, revealing that e-cigarette aerosol, though less cytotoxic to human bronchial epithelial cells, induces distinct transcriptomic signatures with or without added nicotine 28

Most cigar smokers do inhale some amount of smoke and are unaware that they are doing it, even among those who do not intend to inhale

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Daily smokers and nondaily smokers had about twice the odds of relapsing to drug use at the end of the three-year period compared to nonsmokers

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