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Instead, most 210 Po is produced synthetically, through neutron bombardment of 209 Bi in a nuclear reactor

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While the nicotine content of Iqmik and commercial smokeless tobacco products are similar, daily nicotine exposure among Alaska Native Americans was shown to be much higher for Iqmik users compared to both commercial smokeless tobacco users and cigarette smokers 4

Until further research is done, we cant really know how safe e-cigarettes are