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Limitations of the data The indicators presented in this article are derived from self-reported data

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It is the mental addiction that causes the physical feelings and these are caused by the process a smoker/vaper has gone through whilst becoming addicted

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Prior work from our lab has demonstrated that even in the absence of caustic smoking-related stimuli, TCCSUP cell-derived EVs can promote the malignant transformation of immortalized human urothelial SV-HUC cells in a cargo protein-dependent manner 40

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