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10.1016/j.ijdevneu.2017.01.014 83

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"As far as WHO is aware, no rigorous, peer-reviewed studies have been conducted showing that the electronic cigarette is a safe and effective nicotine replacement therapy," the World Health Organization wrote in 2008

Higher concentrations of nicotine in e-cigarettes also poses a threat to young people because vaping nicotine can intensify symptoms of depression and anxiety and increase stress levels

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Johns Hopkins University