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In an attempt to counteract this depletion, cells exposed to cigarette smoke will increase the expression of enzymes involved in the biosynthesis of new GSH (GCLM and GCLC) and the recycling of GSSG to GSH (GSR)

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In recent years, synthetic nicotine products have gained a strong foothold in the local liquid e-cigarettes market, accounting for 92.2 percent of all liquid e-cigarettes in 2022, up from 76 percent in 2020, according to the Korea Health Promotion Institute

Additionally, tobacco use can reduce sensation in the mouth, making it hard to detect early signs of dental problems

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