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Barbiturates, such as mephobarbital (Mebaral ), phenobarbital (Luminal ), and pentobarbital salt (Nembutal ), are made use of much less often to reduce anxiety or to aid with sleep troubles as a result of their greater danger of overdose compared to benzodiazepines

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For beginners, this delayed response often leads to accidental overconsumption, as new users may mistakenly take additional doses before feeling the initial effects