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Hypothalamic-pituitary-adrenal (HPA) axis The fetal hypothalamic-pituitary-adrenal (HPA) axis is critical for mechanisms controlling the regulation of intrauterine homeostasis, the timely differentiation and maturation of vital organ systems such as the CNS, liver, and lungs, preparing the timing of fetal growth, and commencing parturition [37, 38]

It should be used with caution in people taking medications that can lower seizure threshold, such as antidepressants and oral hypoglycaemic agents

This fraction is within the range of other studies, in which a percentage of transfer between 6 and 20% has been determined 22,23 and very close to the most recent study 24 using a smoking machine to determine 210 Po and 210 Pb in the mainstream smoke (13% for 210 Po)

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