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Nose-to-Brain Peptide DeliveryThe Potential of Nanotechnology

doi: 10.1111/j.1600-0447.1992.tb10319.x 50 AlvarezBDMoralesCAAmodeoDA

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Aqueous solutions of poloxamers are stable in the presence of acids, alkalis, and metal ions

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As a result, it compromises the functioning of phospholipid bilayers by creating pores, atomic ion, and molecule leaks, and enhanced permeability, ultimately leading to cell lysis (Jamasbi et al., 2016)