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Of the pathways enriched in the non-smokers, five were responsible for nucleoside synthesis (PWY0-162, PWY-7208, PWY-7228, PWY-7197, and PWY-6609), six were responsible for biosynthesis (PWY-1269, PWY0-1586, PWY-5188, POLYAMSYN-PWY, PWY-7371, and PWY-6305), four were responsible for carbohydrate degradation (PWY66-400, P461-PWY, PWY-1042, and GOLPDLCAT-PWY), three were responsible for degrading amino acids and nucleotides (PWY-7237, PWY-6608, and PWY-6527), and two were responsible for generating precursor metabolites and energy (PWY-5690 and GLYCOLYSIS)
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Stead LF, Perera R, Bullen C, Mant D, Lancaster T (2008)
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Just because the maximum amount legally permitted is 2% nicotine in a single vape or bottle of e-liquid, this isn't to say you can't choose vapes with lower nicotine levels