In the case of e-cigarettes, however, this use has the disadvantage of making the steam generated very irritating (because of the basic nature of the free base nicotine), which limits the amount that can be absorbed during vaping (see Figure 1)
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Buckley et al, 2020) As of January 2021, the FDA had not approved any medications for tocolysis
So far, only one such device -- made by one of the world's largest tobacco companies, Philip Morris International -- has been authorized by the U.S
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