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Certain diseases, such as ischemic heart disease (heart attacks and related coronary artery disease), stroke, chronic lung disease and lung cancer, have been clearly linked to smoking and were found to be the cause of death in approximately 60% of the smokers in these studies

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10.1016/S1474-4422(02)00038-8 175

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Figure 10: State Cigarette Excise Tax Rates by Pack in 2010 This image is excerpted from a U.S

The hypoxia group was additionally pre-incubated at 1% O 2 for 2 h prior to CSE treatment (Fig