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[4] [5] [6] Standard textbooks, databases, and safety sheets consistently state that the lethal dose of nicotine for adults is 60 mg or less (3060 mg), but there is overwhelming data indicating that more than 500 mg of oral nicotine is required to kill an adult

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See also p.151 of the report: Burning Issues: The Global State of Tobacco Harm Reduction 2020

Lao PDR, Myanmar, Philippies and Thailand have long-term policies on the tobacco taxation structure with regular monitoring and adjustments

There was very limited evidence that smoking pot is a slippery slope to a big drug problem