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Airway inflammation, oxidative stress, and lung emphysema are the main mechanisms of the onset of COPD [24]

If desired, treatment options include: Discontinuing responsible drugs Avoiding smoking and excessive alcohol intake Encouraging good oral hygiene Gentle tongue debridement, with a tongue scraper or soft toothbrush and solution containing 3% hydrogen peroxide or baking soda [1] Antiseptic mouthwash Topical antifungal agent for oral Candida albicans if present Topical retinoid If other treatment fails, trimming papillae by carbon dioxide laser burning and electrodessication have been described [5]

It can also occur through kissing if an active cold sore is present on the mouth