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The company would need to receive an MRTP order from the FDA before they could market a tobacco product with any implicit or explicit claims that, among other things, a product reduces exposure to a substance or that use of the product is less harmful or would reduce harm or the risk of disease associated with other commercially marketed tobacco products

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Muscle relaxation - Nicotine intervenes with the muscle relaxation of the esophagus, which leads to gastric efflux Esophageal lining - Nicotine damages the mucus membranes which protect the esophageal lining, which triggers the gastric efflux 2

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